The authors have investigated the effect of pentagastrin and of meat extract on salivary secretion. Both stimuli significantly increase the secretion of saliva. Factors such as taste and deglutition don't influence the increase of salivary secretion due to meat extract, as it remains even when meat extract was administered by naso-gastric tube. This finding suggest that endogenous gastrin, stimulated by meat extract, as well as exogenous pentagastrin, influence the secretion of saliva.