GABA and hippocampal inhibition

Br J Pharmacol. 1970 Dec;40(4):881-3. doi: 10.1111/j.1476-5381.1970.tb10663.x.

Abstract

Bicuculline, a specific GABA antagonist, diminishes basket cell inhibition of hippocampal pyramidal neurones, an inhibition which is not affected by strychnine.The inhibitory transmitter released by basket cells is thus probably GABA.

MeSH terms

  • Action Potentials / drug effects
  • Alanine / antagonists & inhibitors
  • Alanine / pharmacology
  • Aminobutyrates / antagonists & inhibitors*
  • Aminobutyrates / pharmacology
  • Animals
  • Cats
  • Glycine / antagonists & inhibitors
  • Glycine / pharmacology
  • Hippocampus / drug effects*
  • Isoquinolines / pharmacology*
  • Strychnine / pharmacology

Substances

  • Aminobutyrates
  • Isoquinolines
  • Strychnine
  • Alanine
  • Glycine