Massive retinal gliosis simulating choroidal melanoma

Can J Ophthalmol. 1979 Oct;14(4):285-90.


A pigmented fundus lesion in a 47-year-old woman gave a positive 32P test result and angiography showed a separate tumor circulation suggesting a diagnosis of choroidal melanoma. Examination after local resection of the tumor revealed massive retinal gliosis, a rare condition not normally considered in the differential diagnosis of choroidal melanoma. We review the clincial and histologic features that differentiate massive retinal gliosis from choroidal melanoma and astrocytic hamartoma.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Choroid Neoplasms / diagnosis*
  • Diagnosis, Differential
  • Female
  • Gliosis / diagnosis*
  • Gliosis / pathology
  • Humans
  • Melanoma / diagnosis*
  • Middle Aged
  • Retina / ultrastructure
  • Retinal Diseases / diagnosis*
  • Retinal Diseases / pathology