Abstract
After mice were exposed to a daily auditory stressor for varying lengths of time, the responses of their splenic lymphoid cells in vitro were assessed. Both the blastogenic activity of concanavalin A or lipopolysaccharide and the ability of immune lymphocytes to lyse P815 target cells showed the same patterns of immunosuppression and enhancement.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Cytotoxicity Tests, Immunologic
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Humans
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Hydrocortisone / blood
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Immunity, Cellular*
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Immunosuppression Therapy
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Lymphocyte Activation
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Lymphocytes / immunology*
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Male
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Mice
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Mice, Inbred Strains
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Noise
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Spleen / immunology
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Stress, Physiological / blood
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Stress, Psychological / physiology*
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Time Factors