Injections of sclerosing agents into the caudae of the epididymides of adult and prepubertal dogs induced a long-lasting and probably irreversible azoospermia. The technique is easy to do and inexpensive, does not seem to cause undesirable side effects, and appears suitable for large-scale sterilization programs in male dogs.
PIP: Azoospermia in dogs induced by injection of sclerosing agents into the caudae of the epididymides was investigated. Treatment with formalin induced temporary azoospermia or oligospermia in all treated dogs; testicular diameter increased significantly (p less than .05) on Days 5 and 7 after treatment. The 2 dogs teated with 1.5% chlorhexidine gluconate in 50% DMSO became azoospermic for the duration of the study. Treatment with a 3.3% solution of formalin in .05 M phosphate-buffered saline solution induced temporary azoospermia or oligospermia. The technqiue described is effective, easy to apply, inexpensive, does not seem to cause undesirable side effects, and appears suitable for large-scale sterilization in male dogs.