Granulomatous mastitis. A review of 5 cases

S Afr Med J. 1977 Jul 2;52(1):14-6.


A review of 67 cases diagnosed as granulomatous, tuberculous or fungal mastitis revealed 5 cases which were similar, clinically and histopathologically, to the new entity of granulomatous mastitis described by Kessler and Wolloch. The 5 patients were young women of childbearing age, 4 with breast lesions clinically simulating carcinoma of the breast. Histopathological examination showed granulomata and abscess formation confined to the breast lobules. No acid-fast bacilli or fungi were demonstrated. Granulomatous mastitis may be caused by a chemical reaction associated with contraceptive pill therapy, or may have an auto-immune or infective aetiology.

MeSH terms

  • Adolescent
  • Adult
  • Breast / pathology
  • Contraceptives, Oral / adverse effects
  • Female
  • Granuloma / chemically induced
  • Granuloma / etiology
  • Granuloma / pathology
  • Humans
  • Mastitis / chemically induced
  • Mastitis / etiology
  • Mastitis / pathology*
  • Pregnancy


  • Contraceptives, Oral