Concurrent intracranial self-stimulation and amphetamine self-administration in rats

Pharmacol Biochem Behav. 1977 Nov;7(5):459-61. doi: 10.1016/0091-3057(77)90214-3.


In a two-lever testing chamber, rats had concurrent access to intravenous amphetamine and brain stimulation reinforcers. Responding for each reinforcer was generally increased above baseline rates taken when only one reinforcer was available. Amphetamine stereotypy was observed, but did not interfere with rapid lever-pressing for brain stimulation.

MeSH terms

  • Amphetamine*
  • Animals
  • Humans
  • Male
  • Psychopharmacology
  • Rats
  • Self Administration
  • Self Stimulation*
  • Stereotyped Behavior
  • Substance-Related Disorders*


  • Amphetamine