The parabolic dependence of drug action upon lipophilic character as revealed by a study of hypnotics

J Med Chem. 1968 Jan;11(1):1-11. doi: 10.1021/jm00307a001.
No abstract available

MeSH terms

  • Alcohols
  • Alkanes
  • Alkenes
  • Alkynes
  • Amides
  • Animals
  • Barbiturates* / metabolism
  • Benzene Derivatives
  • Chemical Phenomena
  • Chemistry
  • Chlorine
  • Hypnosis
  • Hypnotics and Sedatives*
  • In Vitro Techniques
  • Liver / metabolism
  • Mice
  • Morpholines
  • Solubility
  • Sulfur
  • Water

Substances

  • Alcohols
  • Alkanes
  • Alkenes
  • Alkynes
  • Amides
  • Barbiturates
  • Benzene Derivatives
  • Hypnotics and Sedatives
  • Morpholines
  • Water
  • Chlorine
  • Sulfur