Further improvements in the plaque technique for detecting single antibody-forming cells

Immunology. 1968 Apr;14(4):599-600.


A simple technique for detecting plaque-forming cells is described. It combines the sensitivity and improved optical conditions of the previously reported monolayer technique with the screening power and ease of quantification of the original agar-plate method.

MeSH terms

  • Animals
  • Antibody Formation*
  • Erythrocytes / immunology
  • Goats
  • Immunochemistry*
  • Lymphocytes / immunology
  • Methods
  • Mice
  • Sheep
  • Spleen / cytology*