Study of fatal cases of Friedreich's ataxia

Br Med J. 1968 Sep 14;3(5619):649-52. doi: 10.1136/bmj.3.5619.649.

Abstract

A study of 82 fatal cases of Friedreich's ataxia showed that over half the patients died of heart failure while nearly three-quarters had evidence of cardiac dysfunction during life. A high incidence of diabetes mellitus (23%) was another finding, and four patients developed diabetic ketosis terminally.

MeSH terms

  • Acidosis / complications
  • Adolescent
  • Adult
  • Aged
  • Arrhythmias, Cardiac / complications
  • Child
  • Child, Preschool
  • Diabetes Complications
  • Electrocardiography
  • England
  • Female
  • Friedreich Ataxia / complications*
  • Friedreich Ataxia / genetics
  • Friedreich Ataxia / mortality*
  • Heart Failure / complications
  • Humans
  • Longevity
  • Male
  • Middle Aged
  • Myocardial Infarction / complications
  • Pneumonia / mortality
  • Tachycardia / complications