The reflex sympathetic dystrophy syndrome. II. Roentgenographic and scintigraphic evidence of bilaterality and of periarticular accentuation

Am J Med. 1976 Mar;60(3):332-8. doi: 10.1016/0002-9343(76)90748-8.


Patchy osteoporosis is the primary roentgenologic manifestation of the reflex sympathetic dystrophy syndrome (RSDS). As recent clinical and histologic data suggested articular changes in RSDS, fine-detail roentgenograms were obtained in eight consecutive patients. Juxta-articular and soft-tissue swelling, osteoporosis and erosions of the subchondral bone were found. 99mTcO4 and 99mTc-EHDP scintigraphy showed localization of nuclide predominantly in the juxta-articular tissues. Serial roentgenographic, scintigraphic and quantitative bone densitometric measurements showed changes that reflected the clinical course of the disease.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Densitometry
  • Female
  • Foot / diagnostic imaging
  • Hand / diagnostic imaging
  • Humans
  • Joint Diseases / diagnosis*
  • Joint Diseases / diagnostic imaging
  • Middle Aged
  • Osteoporosis / diagnostic imaging
  • Radiography
  • Radionuclide Imaging
  • Reflex Sympathetic Dystrophy / diagnosis*
  • Reflex Sympathetic Dystrophy / diagnostic imaging
  • Syndrome
  • Technetium


  • Technetium