A study of the fatty acid metabolism of the yeast Pityrosporum ovale

Biochem J. 1968 Jun;108(2):225-31. doi: 10.1042/bj1080225.


The yeast Pityrosporum ovale, a skin saprophyte, will only grow if fatty acids of chain length greater than C(10) are added to the culture medium. 9-Hydroxypalmitic acid is the major product of metabolism of even-carbon-number fatty acids; 9-hydroxystearic acid is also found. The optimum pH for this conversion is pH4.5. The hydroxy fatty acids produced are found bound in a polar form in the aqueous phase of the culture medium. Growth of the organisms is facilitated by presentation of the substrate as a two-phase liquid system.

MeSH terms

  • Chromatography, Gas
  • Chromatography, Thin Layer
  • Fatty Acids / metabolism*
  • Hydrogen-Ion Concentration
  • Mitosporic Fungi / metabolism*
  • Palmitic Acids / biosynthesis
  • Stearic Acids / biosynthesis


  • Fatty Acids
  • Palmitic Acids
  • Stearic Acids