Influence of experimental dietary conditions on hepatic enzymes of glutamic acid metabolism in rats

Nutr Metab. 1975;19(1-2):20-7. doi: 10.1159/000175643.

Abstract

The lowering levels of dietary protein induced a significant fall of some hepatic enzymes associated with glutamic acid metabolism. The changes were later normalised during dietary rehabilitation of the protein-deprived rats. The levels of these enzymes were found to be increased as compared to those observed after starvation, on feeding a carbohydrate-free, protein-rich diet or by the dietary supplementation by glutamic acid.

MeSH terms

  • Alanine Transaminase / metabolism
  • Animals
  • Aspartate Aminotransferases / metabolism
  • Dietary Carbohydrates
  • Dietary Proteins*
  • Glutamate Decarboxylase / metabolism
  • Glutamate-Ammonia Ligase / metabolism
  • Glutaminase / metabolism
  • Liver / drug effects
  • Liver / enzymology*
  • Liver / metabolism
  • Proteins / pharmacology*
  • Rats
  • gamma-Glutamyltransferase / metabolism

Substances

  • Dietary Carbohydrates
  • Dietary Proteins
  • Proteins
  • gamma-Glutamyltransferase
  • Aspartate Aminotransferases
  • Alanine Transaminase
  • Glutaminase
  • Glutamate Decarboxylase
  • Glutamate-Ammonia Ligase