During the early dry season of 1972, an arbovirus surveillance was carried out is Shaki. On hundred and twenty human blood samples and 304 sera were processed for virus isolation and serology respectively. A high prevalence of antibodies to 8 arbovirus antigens was found in the community. Percentage of positive sera was as follows: Chikungunya (24%) Sindbis (19%), Yellow fever (55%), Dengue (54%), West Nile (58%) and Wesselsbron (67%). Human infections by Ilesha virus (35%) and Ingwavuma (15%) were also demonstrated. No virus was isolated from the blood samples processed.