Metabolism of 17beta-hydroxy-2alpha-methyl-5alpha-androstan-3-one in the rabbit

Steroids. 1977 Mar;29(3):371-81. doi: 10.1016/0039-128x(77)90006-x.

Abstract

The neutral urinary excretion products of 17beta-hydroxy-2alpha-methyl-5alpha-androstan-3-one from the rabbit dosed orally were investigated. Together with oxidation-reduction of the oxygen functions at C-3 and C-17 hydroxylation occurred at C-15, C-16, and at the 2alpha-methyl positions of the steroid nucleus.

MeSH terms

  • Androstanols / metabolism*
  • Androstanols / urine
  • Animals
  • Chromatography, Gas
  • Glucuronidase
  • Magnetic Resonance Spectroscopy
  • Male
  • Rabbits

Substances

  • Androstanols
  • Glucuronidase