Clotrimazole vs haloprogin treatment of tinea cruris

Arch Dermatol. 1977 Sep;113(9):1233-5.

Abstract

A study to compare the efficacy of clotrimazole 1% solution with that of haloprogin 1% solution for the treatment of tinea cruris was conducted among military personnel on active duty in a hot, humid climate. Eighty patients with documented dermatophyte infections were treated with the topical antifungal agents. Analysis of the response to treatment for 14 days demonstrated that clotrimazole was significantly more effective clinically and mycologically than haloprogin. With no further treatment, significantly more patients treated with clotrimazole remained free of the disease four weeks later.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Clotrimazole / therapeutic use*
  • Humans
  • Imidazoles / therapeutic use*
  • Male
  • Phenyl Ethers / adverse effects
  • Phenyl Ethers / therapeutic use*
  • Tinea / drug therapy*

Substances

  • Imidazoles
  • Phenyl Ethers
  • Clotrimazole