The pharmacological activity of tribenoside

Pharmacology. 1977;15(5):445-60. doi: 10.1159/000136721.

Abstract

Ethyl-3,5,6-tri-O-benzyl-D-glucofuranoside (RBGF) the active substance of Glyvenol displays a unique spectrum of activities. It possesses anti-inflammatory, mild analgesic, antitoxic, wound-healing, fibrinolysis-promoting, anti-arthrotic, amine-release-inhibitory, membrane-stabilizing and venotropic properties. Unlike corticosteroids or nonsteroidal anti-inflammatory agents, TBGF dose not exert untoward effects on the gastrointestinal system, the connective tissue or the body's defence systems. In addition, TBGF does not affect the prostaglandin-synthetase system. TBGF thus seems to share the positive pharmacological properties ascribed to glucocorticoids and non-steroidal anti-inflammatory agents, yet is free from the undesirable effects of both.

MeSH terms

  • Analgesics
  • Animals
  • Arthritis / drug therapy
  • Cats
  • Cell Membrane / drug effects
  • Erythrocytes / drug effects
  • Fibrinolysis / drug effects
  • Glycosides / pharmacology*
  • Glycosides / therapeutic use
  • Guinea Pigs
  • Humans
  • Hypersensitivity / drug therapy
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Platelet Aggregation / drug effects
  • Rabbits
  • Rats
  • Vascular Resistance / drug effects
  • Wound Healing / drug effects

Substances

  • Analgesics
  • Glycosides