The Effect of Epinephrine on Tracheal Fluid Flow and Surfactant Efflux in Fetal Sheep

Am Rev Respir Dis. 1978 Dec;118(6):1023-6. doi: 10.1164/arrd.1978.118.6.1023.

Abstract

A marked decrease in fetal tracheal fluid flow and an increase in pulmonary surfactant efflux were found after infusion of epinephrine into fetal sheep. The data suggest that endogenous catecholamines may play a role in preparing the fetal lung for birth.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Body Fluids / physiology*
  • Epinephrine / administration & dosage
  • Epinephrine / pharmacology*
  • Fetus / physiology*
  • Gestational Age
  • Infusions, Parenteral
  • Lung / embryology*
  • Lung / metabolism
  • Phosphatidylcholines / analysis
  • Pulmonary Surfactants / metabolism*
  • Sheep
  • Time Factors

Substances

  • Phosphatidylcholines
  • Pulmonary Surfactants
  • Epinephrine