Candida meningitis in the newborn

South Med J. 1979 Nov;72(11):1468-71. doi: 10.1097/00007611-197911000-00036.

Abstract

The incidence of Candida meningitis in the neonatal period is increasing, and 63% of reported patients have either died or are mentally retarded. We report a newborn with Candida meningitis and arthritis who did well after treatment with intravenous and intrathecal amphotericin B, along with oral flucytosine.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Amphotericin B / administration & dosage
  • Amphotericin B / therapeutic use*
  • Arthritis, Infectious / complications
  • Arthritis, Infectious / drug therapy
  • Candidiasis / complications
  • Candidiasis / drug therapy*
  • Cytosine / analogs & derivatives*
  • Drug Therapy, Combination
  • Flucytosine / administration & dosage
  • Flucytosine / therapeutic use*
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases / complications
  • Infant, Newborn, Diseases / drug therapy*
  • Infusions, Parenteral
  • Injections, Spinal
  • Male
  • Meningitis / complications
  • Meningitis / drug therapy*

Substances

  • Amphotericin B
  • Cytosine
  • Flucytosine