Abstract
The incidence of Candida meningitis in the neonatal period is increasing, and 63% of reported patients have either died or are mentally retarded. We report a newborn with Candida meningitis and arthritis who did well after treatment with intravenous and intrathecal amphotericin B, along with oral flucytosine.
MeSH terms
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Administration, Oral
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Amphotericin B / administration & dosage
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Amphotericin B / therapeutic use*
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Arthritis, Infectious / complications
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Arthritis, Infectious / drug therapy
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Candidiasis / complications
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Candidiasis / drug therapy*
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Cytosine / analogs & derivatives*
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Drug Therapy, Combination
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Flucytosine / administration & dosage
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Flucytosine / therapeutic use*
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Humans
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Infant, Newborn
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Infant, Newborn, Diseases / complications
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Infant, Newborn, Diseases / drug therapy*
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Infusions, Parenteral
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Injections, Spinal
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Male
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Meningitis / complications
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Meningitis / drug therapy*
Substances
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Amphotericin B
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Cytosine
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Flucytosine