Desmoplastic trichoepithelioma

Cancer. 1977 Dec;40(6):2979-86. doi: 10.1002/1097-0142(197712)40:6<2979::aid-cncr2820400633>;2-8.


Fifty examples of a distinctive clinicopathologic entity occurred in 49 patients who ranged in age from 8 to 70 (median 46) years. Forty-nine tumors were on the face, mainly the cheek, chin and forehead; most were present one to five years, and 85% of the patients were female. The growths varied in size from 3 to 8 mm; many were hard and annular, with a raised border and depressed nonulcerated center. Histologically, narrow strands of basaloid cells and epidermoid cyts infiltrated a fibrotic stroma. This tumor, which we have named desmoplastic trichoepithelioma, must be differentiated histologically from morphealike basal cell carcinoma, desmoplastic cutaneous metastasis, and certain benign adnexal neoplasms.

MeSH terms

  • Adenoma / pathology
  • Adolescent
  • Adult
  • Aged
  • Breast Neoplasms / pathology
  • Carcinoma, Basal Cell / pathology
  • Child
  • Diagnosis, Differential
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Metastasis / pathology
  • Skin Neoplasms / pathology*
  • Sweat Gland Neoplasms / pathology