LDH isoenzyme pattern in a meningioma with pulmonary metastases

J Pathol. 1977 Nov;123(3):187-91. doi: 10.1002/path.1711230309.


The case is presented of an intraspinal meningioma in a 14-yr-old female. After surgical exploration pulmonary metastases became apparent. At necropsy the tumour had increased proportions of the cathodal isoenzymes LDH-4 and 5. This pattern has previously been observed in malignant meningiomas and may be used at the time of biopsy to assess malignancy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Female
  • Humans
  • Isoenzymes
  • L-Lactate Dehydrogenase / analysis*
  • Lung Neoplasms / pathology*
  • Meningeal Neoplasms / enzymology*
  • Meningeal Neoplasms / pathology
  • Meningioma / enzymology*
  • Meningioma / pathology
  • Neoplasm Metastasis


  • Isoenzymes
  • L-Lactate Dehydrogenase