Ocular histoplasmosis: clinicopathologic correlation of 3 cases

Surv Ophthalmol. 1977 Nov-Dec;22(3):189-205. doi: 10.1016/0039-6257(77)90055-8.

Abstract

The eyes of three patients followed clinically for many years with a diagnosis of macular disciform scarring, secondary to ocular histoplasmosis, were studied histopathologically. A fibrovascular scar interposed between the choroid and retina was observed in all cases. Vessels passing from the choroid through defects in Bruch's membrane into the nodule were demonstrated. Theories of the pathogenesis of the lesion are discussed.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Choroid / pathology
  • Eye Diseases / etiology
  • Eye Diseases / pathology*
  • Eye Diseases / therapy
  • Female
  • Histoplasmosis / complications
  • Histoplasmosis / pathology*
  • Humans
  • Light Coagulation
  • Macula Lutea / pathology*
  • Male
  • Middle Aged
  • Retina / pathology
  • Syndrome