Hepatic clearance of drugs. II. Experimental evidence for acceptance of the "well-stirred" model over the "parallel tube" model using lidocaine in the perfused rat liver in situ preparation

J Pharmacokinet Biopharm. 1977 Dec;5(6):655-80. doi: 10.1007/BF01059689.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Kinetics
  • Lidocaine / metabolism*
  • Liver / metabolism*
  • Models, Biological
  • Rats


  • Lidocaine