Corsi's cube test was given to 40 control and 80 brain-damaged patients to assess the relation of different aspects of spatial memory to the hemispheric locus of lesion. Spatial span was found affected by injury producing visual field defect (VFD), regardless of the side of the lesion. Delayed reproduction of a 3 cube sequence (which was within the span of every patient) was performed more poorly by patients with right hemisphere damage and VFD than by controls. This was true whether the delay was unfilled or filled with a counting activity, the two conditions being equally effective in bringing about the inferiority of the right brain-damaged group. Learning to criterion up to a maximum of 50 trails a supraspan sequence was failed by 65% of right brain-damaged patients with VFD, a percentage significantly higher than that found not only in the control group, but also in any other brain-damaged group. These findings point to the dominant role played by the posterior region of the right hemisphere in subserving spatial memory mechanisms, especially when the acquisition of stable traces is requested.