Beta-lactamase-producing, penicillin-resistant gonococcus

Lancet. 1976 Sep 25;2(7987):656-7. doi: 10.1016/s0140-6736(76)92466-1.

Abstract

A gonococcus was isolated from the vagina of a woman with pelvic inflammatory disease. The organism was typical in all respects except that, unlike any previously described gonococcus, it produced a beta-lactamase that conferred resistance to penicillin, ampicillin, and cephaloridine. Among other antibiotics tested streptomycin was the only one to which the organism was resistant.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Ampicillin / pharmacology
  • Cephaloridine / pharmacology
  • Cephalosporins / pharmacology
  • Female
  • Furans / pharmacology
  • Gonorrhea / microbiology
  • Humans
  • Neisseria gonorrhoeae / drug effects
  • Neisseria gonorrhoeae / enzymology
  • Neisseria gonorrhoeae / isolation & purification
  • Penicillin G / pharmacology
  • Penicillin Resistance
  • Penicillinase / biosynthesis*
  • Penicillinase / isolation & purification
  • Penicillins / pharmacology*

Substances

  • Cephalosporins
  • Furans
  • Penicillins
  • Ampicillin
  • Penicillinase
  • Cephaloridine
  • Penicillin G