DNA sequence and expression of the B95-8 Epstein-Barr virus genome

Nature. 1984 Jul 19-25;310(5974):207-11. doi: 10.1038/310207a0.

Abstract

The complete (172,282 base pairs) nucleotide sequence of the B95-8 strain of Epstein-Barr virus has been established using the dideoxynucleotide/M13 sequencing procedure. Many RNA polymerase II promoters have been mapped and the mRNAs from these promoters have been assigned to the latent or early/late productive virus cycles. Likely protein-coding regions have been identified and three of these have been shown to encode a ribonucleotide reductase, a DNA polymerase and two surface glycoproteins.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • DNA Restriction Enzymes
  • DNA, Viral*
  • Gene Expression Regulation*
  • Genes, Viral*
  • Herpesvirus 4, Human / genetics*
  • RNA Polymerase II / genetics
  • RNA Polymerase III / genetics
  • RNA, Messenger / genetics
  • RNA, Viral / genetics
  • Transcription, Genetic
  • Viral Proteins / genetics

Substances

  • DNA, Viral
  • RNA, Messenger
  • RNA, Viral
  • Viral Proteins
  • RNA Polymerase II
  • RNA Polymerase III
  • DNA Restriction Enzymes

Associated data

  • GENBANK/V01509
  • GENBANK/V01554
  • GENBANK/V01555