Transmission of hepatitis A by transfusion of blood products

Arch Intern Med. 1984 Aug;144(8):1579-80.


The transmission of hepatitis A by blood products has been thought to occur rarely or not at all. By measuring IgM antibody to hepatitis A virus, we diagnosed a case of hepatitis A transmitted by the transfusion of a unit of fresh frozen plasma. Since the commercial availability of methods for measuring IgM antibody to hepatitis A, four other well-defined cases of hepatitis A transmitted by blood products have been reported in the literature. We detail our case and the natural history and importance of this clinical entity.

MeSH terms

  • Adult
  • Antibodies, Viral / immunology*
  • Blood Donors
  • Blood Preservation
  • Child
  • Female
  • Freezing
  • Hepatitis A / immunology
  • Hepatitis A / transmission*
  • Hepatitis A Antibodies
  • Hepatovirus / immunology
  • Humans
  • Infant, Newborn
  • Male
  • Plasma
  • Transfusion Reaction*


  • Antibodies, Viral
  • Hepatitis A Antibodies