In vitro autoradiographic localization of vasoactive intestinal peptide (VIP) binding sites in the rat central nervous system

Peptides. Mar-Apr 1984;5(2):339-40. doi: 10.1016/0196-9781(84)90231-6.

Abstract

This paper describes the autoradiographic distribution of VIP binding sites in the rat central nervous system using monoiodinated 125I-labeled VIP. High densities of VIP binding sites are observed in the granular layer of the dorsal dentate gyrus of the hippocampus, the basolateral amygdaloid nucleus, the dorsolateral and median geniculate nuclei of the thalamus as well as in the ventral part of the hypothalamic dorsomedial nucleus.

MeSH terms

  • Animals
  • Autoradiography
  • Brain / metabolism*
  • Iodine Radioisotopes
  • Rats
  • Rats, Inbred Strains
  • Receptors, Cell Surface / metabolism*
  • Receptors, Vasoactive Intestinal Peptide
  • Tissue Distribution
  • Tritium
  • Vasoactive Intestinal Peptide / metabolism*

Substances

  • Iodine Radioisotopes
  • Receptors, Cell Surface
  • Receptors, Vasoactive Intestinal Peptide
  • Tritium
  • Vasoactive Intestinal Peptide