Small cell neuroendocrine (oat cell) carcinoma of the male breast. Immunocytochemical and ultrastructural investigations

Virchows Arch A Pathol Anat Histopathol. 1984;404(2):213-21. doi: 10.1007/BF00704065.


A case of small cell neuroendocrine (oat cell) carcinoma of the breast in a 52-year old male is presented. Oat cell carcinomas have been reported in various extrapulmonary sites, but this is the second case of a primary oat cell carcinoma of the breast and the first one to have been documented in a male. The tumor was investigated histologically, immunocytochemically and ultrastructurally. The relationship to so-called "carcinoid" mammary tumors is discussed.

Publication types

  • Case Reports

MeSH terms

  • Breast / ultrastructure
  • Breast Neoplasms / ultrastructure*
  • Calcitonin / metabolism
  • Carcinoembryonic Antigen / analysis
  • Carcinoma, Small Cell / ultrastructure*
  • Cytoplasm / ultrastructure
  • Cytoplasmic Granules / ultrastructure
  • Humans
  • Male
  • Middle Aged
  • Phosphopyruvate Hydratase / metabolism


  • Carcinoembryonic Antigen
  • Calcitonin
  • Phosphopyruvate Hydratase