Chickenpox vaccination of healthy children: immunological and clinical responses and protective effect in 1978-1982

Biken J. 1984 Sep;27(2-3):37-8.


A total of 915 normal children without a history of varicella were immunized with a live varicella vaccine (Oka strain) between 1978 and 1982. As clinical reaction after vaccination, fever and or a slight rash was observed in only 10 children. A serological response was observed in all 524 children examined. Of the 854 children who could be followed, 602 children had contact with varicella patients, but extremely mild varicella with a rash developed in only 10 of them. Mild zoster occurred in one child who was admitted to hospital with mycoplasma pneumonia.

MeSH terms

  • Body Temperature
  • Chickenpox / prevention & control*
  • Child
  • Child, Preschool
  • Herpesvirus 3, Human / immunology*
  • Humans
  • Infant
  • Vaccination* / adverse effects
  • Vaccines, Attenuated / immunology
  • Viral Vaccines / immunology*


  • Vaccines, Attenuated
  • Viral Vaccines