Bacterial transposon Tn5: evolutionary inferences

Mol Biol Evol. 1984 Sep;1(5):411-22. doi: 10.1093/oxfordjournals.molbev.a040324.


Transposable elements induce spontaneous mutations, promote genome rearrangements, regulate gene expression, and participate in the horizontal spread of genes encoding traits such as antibiotic resistance among bacterial genera too distantly related to undergo homologous recombination. Here we review the bacterial transposon Tn5 and focus on those aspects of its functional organization and transposition which provide insights into how it and other elements may have arisen, proliferated, and evolved.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Biological Evolution
  • DNA Transposable Elements*
  • Escherichia coli / genetics*
  • Models, Genetic


  • DNA Transposable Elements