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, 1 (8170), 672-4

Effect of Cimetidine on the Gastric Bacterial Flora

  • PMID: 6103090

Effect of Cimetidine on the Gastric Bacterial Flora

W S Ruddell et al. Lancet.

Abstract

Bacteriological studies were carried out on samples of gastric juice obtained from 31 patients with peptic ulcer before and immediately after a month's course of cimetidine. After cimetidine there were major increases in both total bacterial counts and counts of nitrate-reducing organisms and qualitative changes suggesting the establishment of a flora which included large numbers of "faecal" organisms.

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