Predisposition to obesity

Lancet. 1980 May 24;1(8178):1103-4. doi: 10.1016/s0140-6736(80)91552-4.


65 women whose build ranged from normal to grossly obese were investigated to test the hypothesis that obese people, especially those with a genetic predisposition to obesity (manifest by early onset and family history of obesity), have a low energy expenditure. For the group as a whole, resting metabolic rate was related to obesity index, but the age of onset and family history of obesity had no effect on this relationship. The findings suggest that a familial predisposition to obesity is more likely to relate to energy intake than to energy expenditure.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Basal Metabolism
  • Body Weight
  • Child
  • Energy Intake
  • Female
  • Humans
  • Obesity / etiology
  • Obesity / genetics*