[Lethal side effects from ACTH-therapy in infantile spasm (author's transl)]

Monatsschr Kinderheilkd. 1980 Sep;128(9):620-2.
[Article in German]


ACTH in high doses and over long periods of time is the treatment of choice in infantile spasm. Serious side effects can occur, but are not so often described. Two cases are published with hypertonia and immunosuppression. Control of blood pressure and electrolytes is mandatory. The importance of rather careful control of infections is stressed, as symptoms during ACTH-therapy are somewhat altered.

Publication types

  • Case Reports

MeSH terms

  • Adrenocorticotropic Hormone / adverse effects*
  • Adrenocorticotropic Hormone / therapeutic use
  • Humans
  • Hypertension / chemically induced
  • Immunosuppression Therapy
  • Infant
  • Male
  • Spasms, Infantile / drug therapy*


  • Adrenocorticotropic Hormone