Hepatotoxic metabolic activation of paracetamol and its derivatives phenacetin and benorilate: oxygenation or electron transfer?

Biochem Pharmacol. 1981 Mar 1;30(5):399-402. doi: 10.1016/0006-2952(81)90622-5.
No abstract available

MeSH terms

  • Acetaminophen / metabolism*
  • Acetaminophen / toxicity
  • Animals
  • Biotransformation
  • Chemical and Drug Induced Liver Injury / metabolism*
  • Electron Transport
  • Oxidation-Reduction
  • Phenacetin / metabolism
  • Phenacetin / toxicity
  • Salicylates / metabolism
  • Salicylates / toxicity

Substances

  • Salicylates
  • Acetaminophen
  • Phenacetin