Abstract
The effect of porcine insulin has been tested in vitro on human erythrocyte plasma membrane (Na+-K+) and Mg2+-ATPase activities as well as on membrane fluidity. The results indicate that the hormonal treatment significantly inhibits (Na+-K+)-ATPase activity, and at the same time decreases membrane fluidity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenosine Triphosphatases / blood*
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Ca(2+) Mg(2+)-ATPase
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Dose-Response Relationship, Drug
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Erythrocyte Membrane / drug effects*
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Erythrocytes / drug effects*
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Humans
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Insulin / pharmacology*
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Membrane Fluidity / drug effects
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Sodium-Potassium-Exchanging ATPase / antagonists & inhibitors
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Sodium-Potassium-Exchanging ATPase / blood
Substances
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Insulin
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Adenosine Triphosphatases
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Ca(2+) Mg(2+)-ATPase
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Sodium-Potassium-Exchanging ATPase