Insulin effect in vitro on human erythrocyte plasma membrane

Experientia. 1981 Apr 15;37(4):431-3. doi: 10.1007/BF01959904.

Abstract

The effect of porcine insulin has been tested in vitro on human erythrocyte plasma membrane (Na+-K+) and Mg2+-ATPase activities as well as on membrane fluidity. The results indicate that the hormonal treatment significantly inhibits (Na+-K+)-ATPase activity, and at the same time decreases membrane fluidity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphatases / blood*
  • Ca(2+) Mg(2+)-ATPase
  • Dose-Response Relationship, Drug
  • Erythrocyte Membrane / drug effects*
  • Erythrocytes / drug effects*
  • Humans
  • Insulin / pharmacology*
  • Membrane Fluidity / drug effects
  • Sodium-Potassium-Exchanging ATPase / antagonists & inhibitors
  • Sodium-Potassium-Exchanging ATPase / blood

Substances

  • Insulin
  • Adenosine Triphosphatases
  • Ca(2+) Mg(2+)-ATPase
  • Sodium-Potassium-Exchanging ATPase