Evidence that regulation of hepatic guanylate cyclase activity involves interactions between catalytic site -SH groups and both substrate and activator

Arch Biochem Biophys. 1981 Apr 15;208(1):75-86. doi: 10.1016/0003-9861(81)90125-9.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Binding Sites / drug effects
  • Catalysis
  • Chromatography, Gel
  • Enzyme Activation / drug effects
  • Guanylate Cyclase / antagonists & inhibitors
  • Guanylate Cyclase / metabolism*
  • Liver / enzymology*
  • Male
  • Nitroso Compounds / pharmacology
  • Oxidation-Reduction / drug effects
  • Rats
  • Substrate Specificity
  • Sulfhydryl Compounds / pharmacology*

Substances

  • Nitroso Compounds
  • Sulfhydryl Compounds
  • Guanylate Cyclase