Sulfasalazine Inhibits the Absorption of Folates in Ulcerative Colitis

N Engl J Med. 1981 Dec 17;305(25):1513-7. doi: 10.1056/NEJM198112173052506.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Colitis, Ulcerative / metabolism*
  • Female
  • Folic Acid / blood
  • Folic Acid / metabolism*
  • Folic Acid Deficiency / chemically induced
  • Humans
  • Intestinal Absorption / drug effects
  • Jejunum / metabolism
  • Male
  • Middle Aged
  • Pteroylpolyglutamic Acids / metabolism
  • Sulfasalazine / adverse effects*

Substances

  • Pteroylpolyglutamic Acids
  • Sulfasalazine
  • Folic Acid