Ocular manifestations of inflammatory bowel disease

Ann Ophthalmol. 1982 Apr;14(4):356-60.


The association between inflammation of the eyes and the intestine is not often recognized by ophthalmologists. We report two patients who developed peripheral corneal ulcers, episcleritis, and scleritis just prior to the onset of Crohn's disease. The severity of the eye disease paralleled that of the intestinal symptoms, and both conditions subsided after treatment with topical steroids, oral prednisone, oral sulfasalazine, and hydrocortisone retention enemas. Inflammatory bowel disease should always be included in the differential diagnosis of scleritis and uveitis, as the patient may be benefited greatly by appropriate, early therapy of this gastrointestinal disorder.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Corneal Ulcer / complications
  • Crohn Disease / complications*
  • Crohn Disease / drug therapy
  • Eye Diseases / complications*
  • Female
  • Humans
  • Hydrocortisone / therapeutic use
  • Inflammation / complications
  • Intestinal Diseases / complications*
  • Male
  • Prednisone / therapeutic use
  • Sclera
  • Steroids / therapeutic use
  • Sulfasalazine / therapeutic use


  • Steroids
  • Sulfasalazine
  • Prednisone
  • Hydrocortisone