Prospective controlled trial of a Y-connector and disinfectant to prevent peritonitis in continuous ambulatory peritoneal dialysis

Lancet. 1983 Sep 17;2(8351):642-4. doi: 10.1016/s0140-6736(83)92528-x.

Abstract

A controlled study in two centres compared the efficacy of the standard continuous ambulatory peritoneal dialysis (CAPD) system with that of a new method consisting of a Y-shaped set filled with sodium hypochlorite during the dwelling time. 62 new CAPD patients were randomly allocated to the standard method (group A: 30 patients; age 55.5 +/- 17.5 years) or to the Y-system (group B: 32 patients; age 55.1 +/- 14.3 years). In group A, there were 31 peritonitis episodes in 17 patients (57%) during a cumulative period of 351 months--1 episode every 11.3 patient-months. In group B, there were 11 peritonitis episodes in 10 patients (31%) during 363 months--1 episode every 33 patient-months. Life-table analysis showed a significant difference between the incidence of peritonitis in the two groups. The Y-system method is simple and economical and the frequency and the severity of side-effects appears to be acceptable.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Clinical Trials as Topic
  • Disinfectants / pharmacology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Peritoneal Dialysis / methods*
  • Peritoneal Dialysis, Continuous Ambulatory / adverse effects
  • Peritoneal Dialysis, Continuous Ambulatory / instrumentation
  • Peritoneal Dialysis, Continuous Ambulatory / methods*
  • Peritonitis / etiology
  • Peritonitis / prevention & control*
  • Prospective Studies
  • Random Allocation
  • Sodium Hypochlorite / pharmacology

Substances

  • Disinfectants
  • Sodium Hypochlorite