Phosphodiesterase dysfunction, cyclic GMP accumulation, and visual cell degeneration in early-onset inherited blindness

Adv Cyclic Nucleotide Protein Phosphorylation Res. 1984:17:315-27.
No abstract available

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • 3',5'-Cyclic-AMP Phosphodiesterases / deficiency*
  • 3',5'-Cyclic-AMP Phosphodiesterases / metabolism
  • 3',5'-Cyclic-GMP Phosphodiesterases / deficiency*
  • 3',5'-Cyclic-GMP Phosphodiesterases / metabolism
  • Animals
  • Cattle
  • Cyclic GMP / metabolism*
  • Dog Diseases / genetics
  • Dogs
  • Guanosine Triphosphate / physiology
  • Guanylate Cyclase / analysis
  • Guanylate Cyclase / metabolism
  • Hydrolysis
  • Mice
  • Mice, Mutant Strains
  • Phosphoproteins / metabolism
  • Photoreceptor Cells / enzymology*
  • Rabbits
  • Rats
  • Retina / metabolism
  • Retinal Degeneration / genetics*
  • Retinal Degeneration / metabolism
  • Retinal Degeneration / veterinary
  • Rod Cell Outer Segment / enzymology*
  • Rodent Diseases / genetics

Substances

  • Phosphoproteins
  • Guanosine Triphosphate
  • 3',5'-Cyclic-AMP Phosphodiesterases
  • 3',5'-Cyclic-GMP Phosphodiesterases
  • Guanylate Cyclase
  • Cyclic GMP