Outcome of fetal ventriculomegaly

Lancet. 1984 Jul 28;2(8396):179-81. doi: 10.1016/s0140-6736(84)90477-x.

Abstract

Ventriculomegaly was diagnosed in 50 fetuses in the perinatal ultrasound unit of Yale-New Haven Medical Center. The outcomes were elective abortion, 13 (26%); antepartum death, 0 (0%); intrapartum death, 7 (14%); neonatal death within 24 h, 11 (22%); neonatal death after 24 h and within 28 days, 3 (6%); death after 28 days, 2 (4%); survival, 14 (28%). 70% of the deaths were associated with severe congenital anomalies or intrapartum cephalocentesis. Of the 14 survivors, 6 (43%) had Bayley mental or Stanford-Binet scores of over 80, 2 (14%) had scores from 65 to 80, and 6 (43%) had scores of less than 65. The differences in outcome between this antenatal population and previously described neonatal populations with ventriculomegaly may result from the high rate (84%) of abnormalities in association with ventriculomegaly in this study and selection biases in neonatal studies.

MeSH terms

  • Abnormalities, Multiple / diagnosis
  • Abnormalities, Multiple / mortality
  • Abortion, Induced
  • Cerebral Ventricles / embryology
  • Cerebral Ventricles / pathology
  • Cerebrospinal Fluid Shunts
  • Female
  • Fetal Diseases / diagnosis*
  • Fetal Diseases / mortality
  • Humans
  • Hydrocephalus / complications
  • Hydrocephalus / diagnosis*
  • Hydrocephalus / mortality
  • Hydrocephalus / therapy
  • Infant, Newborn
  • Pregnancy
  • Prenatal Diagnosis
  • Ultrasonography