Megascoliakinin, a bradykinin-like compound in the venom of Megascolia flavifrons Fab. (Hymenoptera: Scoliidae)

Comp Biochem Physiol C. 1984;78(2):473-4. doi: 10.1016/0742-8413(84)90116-6.

Abstract

The pharmacological and immunological properties of the venom of Megascolia flavifrons are compared with those of bradykinin and a number of bradykinin analogues. It is postulated that this venom contains a peptide, megascoliakinin, with a bradykinin-like sequence of amino acids, elongated at the C-terminal end with an unknown structure.

MeSH terms

  • Animals
  • Bee Venoms / analysis*
  • Bradykinin / pharmacology
  • Duodenum / drug effects
  • Duodenum / physiology
  • Guinea Pigs
  • In Vitro Techniques
  • Muscle Relaxation / drug effects
  • Muscle, Smooth / drug effects
  • Muscle, Smooth / physiology
  • Wasp Venoms / analysis*
  • Wasp Venoms / pharmacology

Substances

  • Bee Venoms
  • Wasp Venoms
  • megascoliakinin
  • Bradykinin