Nonenzymatic glycosylation of proteins. A warning

J Biol Chem. 1980 Jul 25;255(14):6717-20.

Abstract

Radioactively labeled glucose from several manufacturers contains radioactive impurities of to date unknown structure. These contaminants bind covalently to proteins, e.g. collagen, fibronectin, basic myelin protein, bovine serum albumin, and hemoglobin, and thus simulate nonenzymatic glycosylation.

MeSH terms

  • Animals
  • Cattle
  • Collagen
  • Fibronectins
  • Glucose*
  • Glycosides*
  • Hemoglobin A
  • Humans
  • Kinetics
  • Myelin Basic Protein
  • Protein Binding
  • Proteins*

Substances

  • Fibronectins
  • Glycosides
  • Myelin Basic Protein
  • Proteins
  • Collagen
  • Hemoglobin A
  • Glucose