Amino-terminal amino acid sequence of human leukocyte interferon

Proc Natl Acad Sci U S A. 1980 Sep;77(9):5102-4. doi: 10.1073/pnas.77.9.5102.

Abstract

We report the amino-terminal sequence of the first 22 amino acids of human leukocyte interferon. These and other results indicate that human leukocyte interferon consists of many individual species. We, therefore, postulate that diversity in this protein is routinely present and that the human leukocyte interferons represent a multigene family.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Cells, Cultured
  • Chromatography, High Pressure Liquid
  • Humans
  • Interferons / genetics
  • Interferons / isolation & purification*
  • Leukemia, Myeloid
  • Leukocytes / analysis*
  • Peptide Fragments

Substances

  • Peptide Fragments
  • Interferons