Substance P and opiate-like peptides in human adrenal medulla

Neurosci Lett. 1980 Nov;20(2):195-200. doi: 10.1016/0304-3940(80)90145-7.

Abstract

Opiate-like peptides (OLP), substance P (SP) and catecholamines (CA) were measured in 15 human adrenal medullae. Two groups of subjects were investigated. Group a consisted of subjects who died after traffic accidents and Group b consisted of subjects with other causes of death. OLP levels in Group a were only about 13%, and SP and CA levels about 50% of Group b. It is suggested that these differences might be due to massive premortal adrenal medullary discharge rather than post mortem degradation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenal Medulla / metabolism*
  • Endorphins / metabolism*
  • Enkephalins / metabolism
  • Humans
  • Norepinephrine / metabolism
  • Substance P / metabolism*

Substances

  • Endorphins
  • Enkephalins
  • Substance P
  • Norepinephrine