Abstract
Polynucleotides adsorb on natural and model phospholipid membranes in the presence of Mg2+-cations. Adsorption of nucleic acids on membranes results in a considerable change of their secondary structure. The presence of model phosphatidylcholine membranes greatly stimulates the rate of the synthesis of RNA by E. coli RNA-polymerase on DNA template.
MeSH terms
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Animals
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DNA / metabolism
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DNA-Directed RNA Polymerases / metabolism
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Escherichia coli / enzymology
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Hot Temperature
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Intracellular Membranes / metabolism
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Liposomes / metabolism*
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Methylation
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Mitochondria, Liver / metabolism*
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Phosphatidylcholines / metabolism
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Phospholipids / metabolism
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Polynucleotides / metabolism*
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RNA / biosynthesis
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RNA / metabolism
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Rats
Substances
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Liposomes
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Phosphatidylcholines
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Phospholipids
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Polynucleotides
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RNA
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DNA
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DNA-Directed RNA Polymerases