HLA antigen distribution and HLA haplotype segregation in Crohn's disease

Tissue Antigens. 1980 Jul;16(1):56-61. doi: 10.1111/j.1399-0039.1980.tb00287.x.

Abstract

A study of the HLA-A, -B, -C, and -DR antigens in patients with Crohn's disease and controls did not reveal a significant strong association with a particular HLA antigens. A segregation analysis of parental HLA haplotypes in nine families with at least two children suffering from Crohn's disease did not show a significant deviation from the expected Mendelian segregation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crohn Disease / immunology*
  • Epitopes
  • HLA Antigens*
  • Haploidy*
  • Humans
  • Meiosis*
  • Pedigree

Substances

  • Epitopes
  • HLA Antigens