Raphe pallidus and raphe obscurus projections to the intermediolateral cell column in the rat

Brain Res. 1981 Oct 5;222(1):129-33. doi: 10.1016/0006-8993(81)90946-x.


The descending spinal projections from the raphe pallidus and raphe obscurus nuclei were studied by the anterograde autoradiographic technique in the rat. Both regions project to the intermediolateral cell columns. These pathways were destroyed by intraventricular injections of 5,7-dihydroxytryptamine, a neurotoxin relatively specific for serotonergic cells.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • 5,7-Dihydroxytryptamine / pharmacology
  • Afferent Pathways / anatomy & histology
  • Amino Acids
  • Animals
  • Axonal Transport
  • Brain Stem / anatomy & histology*
  • Horseradish Peroxidase
  • Raphe Nuclei / anatomy & histology*
  • Raphe Nuclei / drug effects
  • Rats


  • Amino Acids
  • 5,7-Dihydroxytryptamine
  • Horseradish Peroxidase