Head circumference as an index of brain weight in the fetus and newborn

Early Hum Dev. 1977 Oct;1(2):145-9. doi: 10.1016/0378-3782(77)90015-9.


Postmortem brain weight and head circumference were measured in 485 fetuses and newborn infants. A cubic relationship was demonstrated between these two variables in normal infants. Statistically, a significantly larger brain weight for a given head circumference was found in small-for-gestational-age infants.

MeSH terms

  • Brain / anatomy & histology*
  • Brain / embryology
  • Cephalometry*
  • Female
  • Humans
  • Infant, Newborn*
  • Infant, Small for Gestational Age
  • Male
  • Mathematics
  • Organ Size
  • Pregnancy